Aging Cell· Jian Chen,
Yuhui Hou,
Ke Ye,
Yilong Guo,
Pingping Sun,
Fangfang Qi,
Zhexiang Fan,
Damao Dai,
Xiaomin Liu,
Shulian Wu,
Demengjie Le,
Zhiqi Hu,
Yong Miao,
Qian Qu·· 4 天前AI 评分18
Aging Cell：衰老真皮白色脂肪组织分泌 MCP-1 经巨噬细胞招募损害毛囊周期，或致年龄相关脱发
MCP‐1 From Aging Dermal Adipose Tissue Impairs Hair Follicle Cycling via Macrophage Recruitment: Implications for Age‐Related Alopecia
AI 导读
小鼠实验显示，衰老真皮白色脂肪组织（dWAT）分泌的 MCP-1 招募巨噬细胞至毛囊周围，破坏局部 M1/M2 平衡并抑制 WNT 信号，损害毛囊周期转换与黑色素生成相关基因表达。
来源：Aging Cell · onlinelibrary.wiley.com